Overview of microRNA biology.

  title={Overview of microRNA biology.},
  author={Ashley M. Mohr and Justin L Mott},
  journal={Seminars in liver disease},
  volume={35 1},
In considering an overview of microRNA biology, it is useful to consider microRNAs as a part of cellular communication. At the simplest level, microRNAs act to decrease the expression of messenger RNAs that contain stretches of sequence complementary to the microRNA. This function can be likened to the function of endogenous or synthetic short interfering RNA. However, microRNA function is more complicated and nuanced than this "on-off" model would suggest. Further, many microRNA targets are… CONTINUE READING

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