Overview of general physiologic features and functions of vitamin D.

  title={Overview of general physiologic features and functions of vitamin D.},
  author={Hector F DeLuca},
  journal={The American journal of clinical nutrition},
  volume={80 6 Suppl},
Vitamin D3 is a prohormone produced in skin through ultraviolet irradiation of 7-dehydrocholesterol. It is biologically inert and must be metabolized to 25-hydroxyvitamin D3 in the liver and then to 1alpha,25-dihydroxyvitamin D3 in the kidney before function. The hormonal form of vitamin D3, ie, 1alpha,25-dihydroxyvitamin D3, acts through a nuclear receptor to carry out its many functions, including calcium absorption, phosphate absorption in the intestine, calcium mobilization in bone, and… CONTINUE READING
Highly Influential
This paper has highly influenced 47 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
628 Citations
62 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 628 extracted citations


Publications referenced by this paper.
Showing 1-10 of 62 references

Fat-soluble vitamins. XVII. The induction of growth-promoting and calcifying properties in a ration by exposure to ultraviolet light

  • H Steenbock, A. Black
  • J Biol Chem 1924;61:405–22
  • 1924
Highly Influential
3 Excerpts

Similar Papers

Loading similar papers…