Overview of general physiologic features and functions of vitamin D.

@article{DeLuca2004OverviewOG,
  title={Overview of general physiologic features and functions of vitamin D.},
  author={Hector F DeLuca},
  journal={The American journal of clinical nutrition},
  year={2004},
  volume={80 6 Suppl},
  pages={1689S-96S}
}
Vitamin D3 is a prohormone produced in skin through ultraviolet irradiation of 7-dehydrocholesterol. It is biologically inert and must be metabolized to 25-hydroxyvitamin D3 in the liver and then to 1alpha,25-dihydroxyvitamin D3 in the kidney before function. The hormonal form of vitamin D3, ie, 1alpha,25-dihydroxyvitamin D3, acts through a nuclear receptor to carry out its many functions, including calcium absorption, phosphate absorption in the intestine, calcium mobilization in bone, and… CONTINUE READING
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Fat-soluble vitamins. XVII. The induction of growth-promoting and calcifying properties in a ration by exposure to ultraviolet light

  • H Steenbock, A. Black
  • J Biol Chem 1924;61:405–22
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