Overview of a 10-year experience on methods and compositions for inducing site-specific immunosuppression with topical immunosuppressants.


Methods and formulations have been successfully developed to bring about site-specific immune suppression of local T-cell-mediated immune responses involved in contact hypersensitivity, skin allograft rejection, and, putatively, autoimmune inflammatory conditions such as psoriasis. The induction of site-specific immune suppression results in reduced… (More)


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