Overview of Mammalian Genome special issue on epigenetics

@article{Peters2009OverviewOM,
  title={Overview of Mammalian Genome special issue on epigenetics},
  author={Jo Peters},
  journal={Mammalian Genome},
  year={2009},
  volume={20},
  pages={529-531}
}
In 1942 C.H. Waddington devised the term ‘‘epigenetics’’ to describe the causal mechanisms of development from the fertilised egg to adult (Waddington 1942). In broad terms this definition still holds, but with time, and increasing knowledge, the term ‘‘epigenetics’’ now covers the study of heritable chromatin modifications that regulate gene expression but do not alter DNA sequence. These modifications comprise modifications of histone proteins and DNA, epigenetic marks that are heritable in… CONTINUE READING

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