Overview of Macrophage Activating Factor and the Nagalase Assay – Potential for Control of Micrometastatic or Early Primary Cancer

Abstract

Macrophage activating factor (GcMAF) functions physiologically to boost the superoxide-generating, phagocytic, and cancerocidal capacities of macrophages; it is generated from vitamin D binding protein by lymphocyte beta-galactosidase and sialidase activities up-regulated by inflammation. Many and possibly most cancers secrete an N-acetylgalactosaminidase… (More)

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