Overview of Data Concerning the Safe Use of Antihyperglycemic Medications in Type 2 Diabetes Mellitus and Chronic Kidney Disease

@article{Roussel2015OverviewOD,
  title={Overview of Data Concerning the Safe Use of Antihyperglycemic Medications in Type 2 Diabetes Mellitus and Chronic Kidney Disease},
  author={Ronan Roussel and Joanne Lorraine and {\'A}ngel Rodr{\'i}guez and Carole Salaun-Martin},
  journal={Advances in Therapy},
  year={2015},
  volume={32},
  pages={1029-1064}
}
IntroductionIt can be a challenge to manage glycemic control in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), due to both patient and medication issues. Although most antihyperglycemic medications can be used in mild kidney disease, many medications are either not advised or require dose adjustments in more advanced CKD. This review summarizes product label information, pharmacokinetic and clinical studies, and clinical guidelines relevant to use of… CONTINUE READING
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