Overview and introduction to clinical proteomics.

@article{Paik2008OverviewAI,
  title={Overview and introduction to clinical proteomics.},
  author={Young-Ki Paik and H Y Kim and Eun-Young Lee and Min-Seok Kwon and Sang Yun Cho},
  journal={Methods in molecular biology},
  year={2008},
  volume={428},
  pages={1-31}
}
As the field of clinical proteomics progresses, discovery of disease biomarkers becomes paramount. However, the immediate challenges are to establish standard operating procedures for both clinical specimen handling and reduction of sample complexity and to increase the ability to detect proteins and peptides present in low amounts. The traditional concept of a disease biomarker is shifting toward a new paradigm, namely, that an ensemble of proteins or peptides would be more efficient than a… CONTINUE READING

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