Overview and Historical Perspectives.

  title={Overview and Historical Perspectives.},
  author={J. Kaper and Alison D. O'Brien},
  journal={Microbiology spectrum},
  volume={2 6}
In this overview, we describe the history of Shiga toxin (Stx)-producing Escherichia coli (STEC) in two phases. In phase one, between 1977 and 2011, we learned that E. coli could produce Shiga toxin and cause both hemorrhagic colitis and the hemolytic-uremic syndrome in humans and that the prototype STEC-E. coli O157:H7-adheres to and effaces intestinal… CONTINUE READING