Overstretching and force-driven strand separation of double-helix DNA.

@article{Cocco2004OverstretchingAF,
  title={Overstretching and force-driven strand separation of double-helix DNA.},
  author={Simona Cocco and Jie Yan and Jean-François L{\'e}ger and Didier Chatenay and John Frederick Daniel Marko},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2004},
  volume={70 1 Pt 1},
  pages={011910}
}
We analyze whether the "overstretched," or "S" form of double-stranded DNA consists of essentially separated, or essentially interacting, polynucleotide strands. Comparison of force-extension data for S-DNA and single-stranded DNA shows S-DNA to be distinct from both double helix and single-stranded forms. We use a simple thermodynamical model for tension-melted double-stranded DNA, which indicates that the overstretching transition near 65 piconewtons cannot be explained in terms of conversion… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
42 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 42 extracted citations

Similar Papers

Loading similar papers…