Overnight verbal memory retention correlates with the number of sleep spindles

  title={Overnight verbal memory retention correlates with the number of sleep spindles},
  author={Zs{\'o}fia Clemens and D{\'a}niel Fab{\'o} and P{\'e}ter Hal{\'a}sz},
Declarative memory performance is associated with the number of sleep spindles in elderly women.
  • M. Seeck-Hirschner, P. Baier, R. Göder
  • Psychology
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 2012
The data strongly support theories suggesting a link between sleep spindle activity and declarative memory consolidation.
Involvement of spindles in memory consolidation is slow wave sleep-specific.
Assessment of declarative memory retention over an interval containing a nap and spindle density showed a strong and robust positive correlation with retention, suggesting that the potentiating effects of spindles are tied to their co-occurrence with slow oscillations.
Involvement of sleep spindles in overnight declarative memory stabilization
ObjectiveNumerous studies point to the involvement of sleep spindles and slow waves in memory processes, particularly in hippocampus-dependent declarative memory. We have shown previously that the
The memory function of sleep
Sleep has been identified as a state that optimizes the consolidation of newly acquired information in memory, depending on the specific conditions of learning and the timing of sleep, through specific patterns of neuromodulatory activity and electric field potential oscillations.
Individual baseline memory performance and its significance for sleep-dependent memory consolidation
Today, there is little doubt concerning the significance of sleep for memory consolidation. Some studies have suggested, however, that overnight memory consolidation as well as their underpinning
The Critical Role of Sleep Spindles in Hippocampal-Dependent Memory: A Pharmacology Study
A critical role of spindles in human hippocampal memory performance is demonstrated for the first time and gains in memory consolidation exceed sleep-alone or control conditions and demonstrate the potential for targeted, exceptional memory enhancement in healthy adults with pharmacologically modified sleep.
Memory consolidation in fragmented sleep
Despite the small sample size, these results provide a first hint toward the involvement of sleep spindles in memory consolidation in patients suffering from severe OSA.


Learning-Dependent Increases in Sleep Spindle Density
Results indicate that spindle activity during non-REM sleep is sensitive to previous learning experience, and spindle density was correlated to recall performance both before and after sleep.
Low acetylcholine during slow-wave sleep is critical for declarative memory consolidation
  • S. Gais, J. Born
  • Biology, Psychology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2004
Increasing central nervous cholinergic activation during SWS-rich sleep by posttrial infusion of 0.75 mg of the cholinesterase inhibitor physostigmine completely blocked SWs-related consolidation of declarative memories for word pairs in human subjects, in line with predictions that a low Cholinergic tone duringSWS is essential forDeclarative memory consolidation.
Sleep states and memory processes
Effects of Early and Late Nocturnal Sleep on Declarative and Procedural Memory
The experiments for the first time dissociate specific effects of early and late sleep on two principal types of memory, declarative and procedural, in humans, and the benefit from sleep on recall depended on the phase of sleep and on the type of memory.
Effects of early and late nocturnal sleep on priming and spatial memory.
It appears that earlySleep dominated by SWS facilitates consolidation of declarative memory whereas late sleep dominated by REM sleep facilitates consolidationof nondeclarativeMemory.
Sleep: off-line memory reprocessing
  • R. Stickgold
  • Psychology, Biology
    Trends in Cognitive Sciences
  • 1998
Sleep spindles: an overview.
This review summarizes the present knowledge on visually scored and automatically detected spindles, as well as the literature on EEG power in the sigma band, and discusses the role of melatonin as a spindle-promoting agent and the relationships between plastic mechanisms.
Communication between neocortex and hippocampus during sleep in rodents
A robust correlation of neuronal discharges between the somatosensory cortex and hippocampus on both slow and fine time scales in the mouse and rat is shown, suggesting that oscillation-mediated temporal links coordinate specific information transfer between neocortical and hippocampal cell assemblies.
Walking through a Maze Alters the Architecture of Sleep
Alteration in temporal architecture of sleep and selective prolongation of sleep Stage 2 following spatial orientation point to a functional linkage between cognitive mapping of space and sleep Stage 1 with enhanced EEG spindle activity is studied.