Overnight changes in waking auditory evoked potential amplitude reflect altered sleep homeostasis in major depression.

@article{Goldstein2012OvernightCI,
  title={Overnight changes in waking auditory evoked potential amplitude reflect altered sleep homeostasis in major depression.},
  author={Michael R Goldstein and David T. Plante and Brad K Hulse and Simone Sarasso and Eric Carl Landsness and Giulio Tononi and Ruth M. Benca},
  journal={Acta psychiatrica Scandinavica},
  year={2012},
  volume={125 6},
  pages={468-77}
}
OBJECTIVE Sleep homeostasis is altered in major depressive disorder (MDD). Pre- to postsleep decline in waking auditory evoked potential (AEP) amplitude has been correlated with sleep slow wave activity (SWA), suggesting that overnight changes in waking AEP amplitude are homeostatically regulated in healthy individuals. This study investigated whether the overnight change in waking AEP amplitude and its relation to SWA is altered in MDD. METHOD Using 256-channel high-density… CONTINUE READING

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