Overfeeding-induced ovarian dysfunction in broiler breeder hens is associated with lipotoxicity.

@article{Chen2006OverfeedinginducedOD,
  title={Overfeeding-induced ovarian dysfunction in broiler breeder hens is associated with lipotoxicity.},
  author={Shenchang Eric Chen and John P. Mcmurtry and Rosemary L. Walzem},
  journal={Poultry science},
  year={2006},
  volume={85 1},
  pages={
          70-81
        }
}
In mammals, triacylglycerol (TAG) accumulation in nonadipose tissue, termed lipotoxicity, develops with obesity and can provoke insulin resistance, overt diabetes, and ovarian dysfunction. Leptin, an adipose tissue hormone, may mediate these effects. Feed-satiated broiler breeder hens manifest lipotoxicity-like symptoms. Changes in body and organ weights, hepatic and plasma TAG, nonesterified fatty acids (NEFA), ovarian morphology, and egg production in response to acute voluntary increases of… CONTINUE READING

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