Overexpression of vimentin contributes to prostate cancer invasion and metastasis via src regulation.

  title={Overexpression of vimentin contributes to prostate cancer invasion and metastasis via src regulation.},
  author={Juncheng Wei and Gang Xu and Mingfu Wu and Yongtao Zhang and Qiong Li and Ping Liu and Tao Zhu and Anping Song and Liangpin Zhao and Zhiqiang Han and Gang Chen and Li Meng and Jianfeng Zhou and Yunping Lu and Shixuan Wang and Ding Ma},
  journal={Anticancer research},
  volume={28 1A},
A significant proportion of prostate cancer patients treated with curative intent develop advanced disease. At a fundamental biological level, very little is known about what makes the disease aggressive and metastatic. Observational pathology reports and experimental data suggest that an epithelial-mesenchymal transition (EMT) is involved in prostate cancer invasiveness. The mechanism by which vimentin promotes prostate cancer cell invasion and metastasis was examined. The highly metastatic… CONTINUE READING


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