Overexpression of tumor necrosis factor (TNF)α and TNFα receptor I in human viral myocarditis: clinicopathologic correlations

Proinflammatory cytokines, including tumor necrosis factor (TNF)α, have been recognized as important physiopathogenetic factors in the initiation and continuation of inflammatory cardiomyopathies. Experimental and preliminary human studies have demonstrated that TNFα plays a crucial role in enteroviral-induced myocarditis. In this study, we investigated the… CONTINUE READING