Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

Abstract

Obesity is accompanied by complications such as hypertension, non–insulin–dependent diabetes mellitus and atherosclerosis, which in turn cause ischaemic heart disease, stroke and premature death1–3. The underlying mechanisms behind imbalance in energy intake and energy expenditure that lead to obesity are still controversial. In most populations, obesity is… (More)
DOI: 10.1038/nm0995-950

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