Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice.

@article{Grizenkova2012OverexpressionOT,
  title={Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice.},
  author={Julia Grizenkova and Shaheen Akhtar and Holger Hummerich and Andrew Stephen Tomlinson and Emmanuel A. Asante and Adam Wenborn and J{\'e}r{\'e}mie Fizet and M. J. Poulter and Frances K. Wiseman and Elizabeth M. C. Fisher and Victor L. J. Tybulewicz and Sebastian Brandner and John Collinge and Sarah E. Lloyd},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 34},
  pages={13722-7}
}
Prion diseases are fatal neurodegenerative disorders that include bovine spongiform encephalopathy (BSE) and scrapie in animals and Creutzfeldt-Jakob disease (CJD) in humans. They are characterized by long incubation periods, variation in which is determined by many factors including genetic background. In some cases it is possible that incubation time may… CONTINUE READING
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