Overexpression of the ATP-dependent helicase RecG improves resistance to weak organic acids in Escherichia coli

@article{Steiner2003OverexpressionOT,
  title={Overexpression of the ATP-dependent helicase RecG improves resistance to weak organic acids in Escherichia coli},
  author={Peter Steiner and Uwe Sauer},
  journal={Applied Microbiology and Biotechnology},
  year={2003},
  volume={63},
  pages={293-299}
}
Increased resistance to several weak organic acids was conferred on Escherichia coli by overexpression of the ATP-dependent helicase RecG and, to a lesser extent, by overexpressing the helicase RuvAB. This property of helicases was identified by reproducible selection of recG-bearing clones from genomic libraries of the acetate-resistant species Acetobacter aceti and Staphylococcus capitis. We show that overexpression of RecG from both species, but also from E. coli, increased the maximum… CONTINUE READING

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Trends in genetics : TIG • 2002
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