Overexpression of profilin reduces the migration of invasive breast cancer cells.

@article{Roy2004OverexpressionOP,
  title={Overexpression of profilin reduces the migration of invasive breast cancer cells.},
  author={Partha Roy and Ken Jacobson},
  journal={Cell motility and the cytoskeleton},
  year={2004},
  volume={57 2},
  pages={84-95}
}
The exact role profilin plays in cell migration is not clear. In this study, we have evaluated the effect of overexpression of profilin on the migration of breast cancer cells. Overexpression was carried out by stably expressing GFP-profilin in BT474 cells. It was observed that even a moderate level of overexpression of profilin significantly impaired the… CONTINUE READING