Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma.

  title={Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma.},
  author={Vuokko L. Kinnula and Sanna Lehtonen and Raija T. Sormunen and Riitta L Kaarteenaho-Wiik and Sang Won Kang and Sue Goo Rhee and Ylermi M Soini},
  journal={The Journal of pathology},
  volume={196 3},
Peroxiredoxins (Prxs) are a recently characterized group of thiol-containing proteins with efficient antioxidant capacity, capable of consuming hydrogen peroxide in living cells. Altogether six distinct Prxs have been characterized in mammalian tissues. Their expression was investigated in histological samples of mesothelioma and in cell lines established from the tumours of mesothelioma patients. Four cases with histopathologically healthy pleura from non-smokers were used as controls. Healthy… CONTINUE READING


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