Overexpression of p53 protein and point mutation of K-ras genes in primary carcinoma of the small intestine.

@article{Nishiyama2002OverexpressionOP,
  title={Overexpression of p53 protein and point mutation of K-ras genes in primary carcinoma of the small intestine.},
  author={Ken-ichi Nishiyama and Takashi Yao and Hirotoshi Yonemasu and Koji Yamaguchi and Masao Tanaka and Masazumi Tsuneyoshi},
  journal={Oncology reports},
  year={2002},
  volume={9 2},
  pages={293-300}
}
Primary carcinoma of the small intestine is rare and represent about 0.5% of all gastrointestinal malignancies. The aim of this study was to examine the biological characteristics of primary carcinoma of the small intestine by immunohistochemical and nested polymerase chain reaction methods. Thirty-five primary carcinomas (12 in the duodenum and 23 in the jejunum or ileum) from 35 patients were studied clinicopathologically and examined for overexpression of p53 protein. In 22 of these 35 cases… CONTINUE READING

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