Overexpression of matrix metalloproteinases and their inhibitors in mononuclear inflammatory cells in breast cancer correlates with metastasis-relapse

@article{Gonzlez2007OverexpressionOM,
  title={Overexpression of matrix metalloproteinases and their inhibitors in mononuclear inflammatory cells in breast cancer correlates with metastasis-relapse},
  author={Luis Ovidio Gonz{\'a}lez and Iv{\'a}n Pidal and Sara Junquera and Mar{\'i}a Daniela Corte and Julio V{\'a}zquez and Juan Carlos Campo Rodriguez and Maria Luz Lamelas and Antonio Mart{\'i}nez Merino and Jos{\'e} Luis Garc{\'i}a-Mu{\~n}iz and Francisco J Vizoso},
  journal={British Journal of Cancer},
  year={2007},
  volume={97},
  pages={957 - 963}
}
An immunohistochemical study was performed using tissue microarrays and specific antibodies against matrix metalloproteinase (MMP)-1, -2, -7, -9, -11, -13 and –14, tissular inhibitors of metalloproteinase (TIMP)-1, -2 and -3. More than 2600 determinations on cancer specimens from 131 patients with primary ductal invasive tumours of the breast were performed. To identify specific groups of tumours with distinct expression profiles the data were analysed by unsupervised hierarchical cluster… CONTINUE READING
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