Overexpression of long non-coding RNA HOTAIR predicts a poor prognosis in patients with acute myeloid leukemia.

@article{Wu2015OverexpressionOL,
  title={Overexpression of long non-coding RNA HOTAIR predicts a poor prognosis in patients with acute myeloid leukemia.},
  author={Shenghao Wu and Cuiping Zheng and Songyan Chen and Xiaoping Cai and Yuejian Shi and Bijing Lin and Yuemiao Chen},
  journal={Oncology letters},
  year={2015},
  volume={10 4},
  pages={2410-2414}
}
The long non-coding RNA, HOX transcript antisense intergenic RNA (HOTAIR), has been indicated to have involvement in a number of cancers, however, its role in acute myeloid leukemia (AML) is unknown. The present study aimed to investigate the pattern of HOTAIR expression in AML and to evaluate its clinical significance in tumor progression. Quantitative polymerase chain reaction was performed to examine the HOTAIR expression in mononuclear cells from the bone marrow (BM) or peripheral blood… CONTINUE READING
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