Overexpression of intestinal trefoil factor in human colon carcinoma cells reduces cellular growth in vitro and in vivo.

@article{Uchino2000OverexpressionOI,
  title={Overexpression of intestinal trefoil factor in human colon carcinoma cells reduces cellular growth in vitro and in vivo.},
  author={Hirofumi Uchino and Hiroaki Kataoka and Hiroshi Itoh and Ryouichi Hamasuna and Masashi Koono},
  journal={Gastroenterology},
  year={2000},
  volume={118 1},
  pages={60-9}
}
BACKGROUND & AIMS Intestinal trefoil factor (ITF) has a role in gastrointestinal mucosal integrity and the repair of damaged mucosa. However, little is known about its role in tumors. To analyze the role of ITF in colon carcinomas, overexpression of the ITF gene in colon carcinoma cells was used. METHODS Human colon carcinoma cell lines LoVo and SW837… CONTINUE READING