Overexpression of histamine H4 receptors in the kidney of diabetic rat

  title={Overexpression of histamine H4 receptors in the kidney of diabetic rat},
  author={Arianna Carolina Rosa and Cristina Grange and Alessandro Pini and Mwape Katebe and Elisa Benetti and Massimo Collino and Gianluca Miglio and Daniele Bani and Giovanni Camussi and Paul Louis Chazot and Roberto Fantozzi},
  journal={Inflammation Research},
The renal expression of H1 and H2 receptors has previously been demonstrated, while that of the H4 receptor has been poorly investigated, and thus the aim of this research was to investigate the expression of the H4 receptor in the kidney of diabetic rats. 24 8-week-old male Wistar rats. Diabetes was induced in 12 rats by a single intravenous injection of streptozotocin, and animals were killed 6 weeks later. Kidneys were collected and processed for quantitative PCR or immunohistochemical… CONTINUE READING
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