Overexpression of high mobility group protein B1 correlates with the proliferation and metastasis of lung adenocarcinoma cells.

@article{Sun2013OverexpressionOH,
  title={Overexpression of high mobility group protein B1 correlates with the proliferation and metastasis of lung adenocarcinoma cells.},
  author={Ke-kang Sun and Cheng Ji and Xing Li and Lu Zhang and Jun Deng and Ning Zhong and Xiao-yang Wu},
  journal={Molecular medicine reports},
  year={2013},
  volume={7 5},
  pages={1678-82}
}
High mobility group protein B1 (HMGB1) plays an important role in a number of clinical conditions, such as autoimmunity, cardiovascular disease and cancer. Evidence suggests that HMGB1 is critical in the development and progression of numerous types of tumor. However, the underlying molecular mechanisms for the HMGB1-mediated progression and metastasis of lung cancer have not yet been elucidated. In this study, we investigated the role of HMGB1 in lung adenocarcinoma and the mechanisms by which… CONTINUE READING

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