Overexpression of gK in gK-transformed cells collapses the Golgi apparatus into the endoplasmic reticulum inhibiting virion egress, glycoprotein transport, and virus-induced cell fusion.

Abstract

Intracellular transport and egress of alphaherpesviruses require the coordinate function of multiple proteins and glycoproteins. Recently, we showed that gK is expressed on infected cell surfaces and that gK cell-surface expression required the presence of the UL20 protein [J. Virol. 77 (2003), 499]. Overexpression of gK by gK-transformed cells blocked… (More)

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@article{Foster2003OverexpressionOG, title={Overexpression of gK in gK-transformed cells collapses the Golgi apparatus into the endoplasmic reticulum inhibiting virion egress, glycoprotein transport, and virus-induced cell fusion.}, author={Timothy P. Foster and Galena V Rybachuk and Xavier Alvarez and Olga N Borkhsenious and Konstantin Gus Kousoulas}, journal={Virology}, year={2003}, volume={317 2}, pages={237-52} }