Overexpression of forkhead box C1 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma.

@article{Xia2013OverexpressionOF,
  title={Overexpression of forkhead box C1 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma.},
  author={Limin Xia and Wenjie Huang and Dean Tian and Hongwu Zhu and Xingshun Qi and Zheng Chen and Yongguo Zhang and Hao Hu and Dai-ming Fan and Yongzhan Nie and Kaichun Wu},
  journal={Hepatology},
  year={2013},
  volume={57 2},
  pages={610-24}
}
UNLABELLED Recurrence and metastasis remain the most common causes of lethal outcomes in hepatocellular carcinoma (HCC) after curative resection. Thus, it is critical to discover the mechanisms underlying HCC metastasis. Forkhead box C1 (FoxC1), a member of the Fox family of transcription factors, induces epithelial-mesenchymal transition (EMT) and promotes epithelial cell migration. However, the role of FoxC1 in the progression of HCC remains unknown. Here, we report that FoxC1 plays a… CONTINUE READING
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