Overexpression of cyclooxygenase-2 as a biomarker in different subtypes of the oral lichenoid disease.

@article{CortsRamrez2010OverexpressionOC,
  title={Overexpression of cyclooxygenase-2 as a biomarker in different subtypes of the oral lichenoid disease.},
  author={Dionisio A. Cort{\'e}s-Ram{\'i}rez and Maria Jose Rodriguez-Tojo and Maria Luisa Gainza-Cirauqui and Rafael Mart{\'i}nez-Conde and Jos{\'e} Manuel Aguirre-Ur{\'i}zar},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2010},
  volume={110 6},
  pages={738-43}
}
OBJECTIVE Oral lichenoid disease (OLD) includes a number of chronic inflammatory processes including oral lichen planus (OLP) and oral lichenoid lesions (OLL) with controversial diagnosis and prognosis. Cyclooxygenase-2 (COX-2) is a key enzyme for inflammatory processes and cellular proliferation. Its overexpression in some premalignant chronic inflammatory diseases and malignant neoplasias could point to its potential as a prognostic factor. The aim of this study was to analyze the COX-2… CONTINUE READING

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