Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus.

Abstract

Cellular prion protein (PrP(C)) is an ubiquitously expressed glycoprotein whose roles are still widely discussed, particularly in the field of immunology. Using TgA20- and Tg33-transgenic mice overexpressing PrP(C), we investigated the consequences of this overexpression on T cell development. In both models, overexpression of PrP(C) induces strong… (More)

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Cite this paper

@article{JouvinMarche2006OverexpressionOC, title={Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus.}, author={Evelyne Jouvin-Marche and Val{\'e}rie Attuil-Audenis and Catherine Aude-Garcia and Walid Rachidi and Mark D Zabel and Val{\'e}rie Podevin-Dimster and Carole Siret and Christoph Huber and Marianne M Martinic and Jacqueline Riondel and Christian L. Villiers and Alain Emile Favier and Philippe Naquet and J. Cesbron and Patrice N Marche}, journal={Journal of immunology}, year={2006}, volume={176 6}, pages={3490-7} }