Overexpression of an alpha 1H (Cav3.2) T-type calcium channel during neuroendocrine differentiation of human prostate cancer cells.

@article{Mariot2002OverexpressionOA,
  title={Overexpression of an alpha 1H (Cav3.2) T-type calcium channel during neuroendocrine differentiation of human prostate cancer cells.},
  author={Pascal Mariot and Karine Vanoverberghe and Nathalie Lalev{\'e}e and Michel Florian Rossier and Natalia Prevarskaya},
  journal={The Journal of biological chemistry},
  year={2002},
  volume={277 13},
  pages={10824-33}
}
Neuroendocrine differentiation of prostate epithelial cells is usually associated with an increased aggressivity and invasiveness of prostate tumors and a poor prognosis. However, the molecular mechanisms involved in this process remain poorly understood. We have investigated the possible expression of voltage-gated calcium channels in human prostate cancer epithelial LNCaP cells and their modulation during neuroendocrine differentiation. A small proportion of undifferentiated LNCaP cells… CONTINUE READING

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