Overexpression of a host factor TOM1 inhibits tomato mosaic virus propagation and suppression of RNA silencing.


A plant integral membrane protein TOM1 is involved in the multiplication of Tomato mosaic virus (ToMV). TOM1 interacts with ToMV replication proteins and has been suggested to tether the replication proteins to the membranes where the viral RNA synthesis takes place. We have previously demonstrated that inactivation of TOM1 results in reduced ToMV… (More)
DOI: 10.1016/j.virol.2008.03.020


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