Overexpression of YKL-40 is an independent prognostic marker in gastric cancer.

@article{Bi2009OverexpressionOY,
  title={Overexpression of YKL-40 is an independent prognostic marker in gastric cancer.},
  author={Jiong Bi and Sze-hang Lau and Zi-Li Lv and Dan Xie and Wen Mei Li and Y Lai and Jue-Min Zhong and Hui-qun Wu and Q. Z. Su and Yulong He and Wen-hua Zhan and Jian-ming Wen and Xinyuan Guan},
  journal={Human pathology},
  year={2009},
  volume={40 12},
  pages={1790-7}
}
YKL-40 is a growth factor for connective tissue cells and a migration factor for endothelial cells. Elevated serum level of YKL-40 has been associated with poor prognosis in many cancers. However, the status of YKL-40 expression and its clinical/prognostic significance in gastric cancer are unclear. In this study, the expression of YKL-40 was studied by immunohistochemistry in gastric cancer tissue microarray containing 172 primary gastric cancer cases and 70 adjacent nonneoplastic mucosa… CONTINUE READING
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