Overexpression of X-linked Inhibitor of Apoptosis Protein (XIAP) is an Independent Unfavorable Prognostic Factor in Childhood de Novo Acute Myeloid Leukemia

@inproceedings{Sung2009OverexpressionOX,
  title={Overexpression of X-linked Inhibitor of Apoptosis Protein (XIAP) is an Independent Unfavorable Prognostic Factor in Childhood de Novo Acute Myeloid Leukemia},
  author={Ki Woong Sung and Jaewon Choi and Yu Kyeong Hwang and Sang Jin Lee and Hee-Jin Kim and Ju Youn Kim and Eun Joo Cho and Keon Hee Yoo and Hong Hoe Koo},
  booktitle={Journal of Korean medical science},
  year={2009}
}
The overexpression of X-linked inhibitor of apoptosis protein (XIAP), a member of IAP family protein, is intuitively expected to be associated with unfavorable clinical features in malignancies; however, there have been only a very limited number of studies reporting the clinical relevance of XIAP expression. This study was performed to investigate the prognostic relevance of XIAP expression in childhood acute myeloid leukemia (AML). In 53 children with de novo AML, the level of XIAP expression… CONTINUE READING
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