Overexpression of TROP2 Predicts Poor Prognosis of Patients with Cervical Cancer and Promotes the Proliferation and Invasion of Cervical Cancer Cells by Regulating ERK Signaling Pathway

@inproceedings{Liu2013OverexpressionOT,
  title={Overexpression of TROP2 Predicts Poor Prognosis of Patients with Cervical Cancer and Promotes the Proliferation and Invasion of Cervical Cancer Cells by Regulating ERK Signaling Pathway},
  author={Ting Liu and Yueyang Liu and Xiangxiang Bao and Jiguang Tian and Yang Liu and Xingsheng Yang},
  booktitle={PloS one},
  year={2013}
}
Overwhelming evidence has demonstrated that the aberrant expression of the human trophoblast cell-surface antigen (TROP2) was associated with tumor aggressiveness and poor prognosis in a variety of human cancers, however the roles of TROP2 in cervical cancer have not been investigated. The purpose of our study was to elucidate the prognostic significance of TROP2 expression in patients with cervical cancer and determine its effect on tumor progression. Immunohistochemistry assay showed that 88… CONTINUE READING

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Current opinion in cervix carcinoma

  • S Rodriguez Villalba, C Diaz-Caneja Planell, JM Cervera Grau
  • Clin Transl Oncol
  • 2011
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