Overexpression of S-adenosylmethionine decarboxylase (SAMDC) activates the maternal program of apoptosis shortly after MBT in Xenopus embryos.

@article{Kai2000OverexpressionOS,
  title={Overexpression of S-adenosylmethionine decarboxylase (SAMDC) activates the maternal program of apoptosis shortly after MBT in Xenopus embryos.},
  author={Munenori Kai and Takayasu Higo and Jun'ichi Yokoska and Chikara Kaito and Emi Kajita and Hiroshi Fukamachi and Eiji Takayama and Kazuei Igarashi and Koichiro Shiokawa},
  journal={The International journal of developmental biology},
  year={2000},
  volume={44 5},
  pages={507-10}
}
Overexpression of S-adenosylmethionine decarboxylase (SAMDC) mRNA in 1- and 2-cell stage Xenopus embryos induces cell autonomous dissociation at the late blastula stage and developmental arrest at the early gastrula stage. The induction of cell dissociation took place "punctually" at the late blastula stage in the SAMDC-overexpressing cells, irrespective of the stage of the microinjection of SAMDC mRNA. When we examined the cells undergoing the dissociation, we found that they were TUNEL… CONTINUE READING

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