Overexpression of RhoE Has a Prognostic Value in Non–Small Cell Lung Cancer

  title={Overexpression of RhoE Has a Prognostic Value in Non–Small Cell Lung Cancer},
  author={Cuiyan Zhang and Fang Zhou and Ning Li and Susheng Shi and Xiaoli Feng and Zhaoli Chen and Jie Hang and Bin Qiu and Baozhong Li and Sheng Chieh Chang and Junting Wan and Kang Shao and Xuezhong Xing and Xiaogang Tan and Zhen Wang and Meihua Xiong and Jie He},
  journal={Annals of Surgical Oncology},
Increasing evidence has suggested that RhoE plays an important role in carcinogenesis and progression. However, the correlation between RhoE expression and clinical outcome in lung cancer has not been investigated. RhoE expression was detected by immunohistochemistry on tissue microarray containing samples from 115 patients with non–small cell lung cancer with a median follow-up of 54 months. RhoE was overexpressed in the cytoplasm of lung cancer cells compared with undetectable expression of… CONTINUE READING


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