Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice.

@article{Ohnishi1997OverexpressionOR,
  title={Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice.},
  author={Hirohide Ohnishi and Linda C. Samuelson and David I. Yule and Stephen A. Ernst and John A. Williams},
  journal={The Journal of clinical investigation},
  year={1997},
  volume={100 12},
  pages={3044-52}
}
Rab3D, a member of the ras-related GTP-binding protein Rab family, is localized to secretory granules of various exocrine tissues such as acinar cells of the pancreas, chief cells of the stomach, and parotid and lacrimal secretory cells. To elucidate the function of Rab3D in exocytosis, we have generated transgenic mice that over-express Rab3D specifically… CONTINUE READING