Overexpression of NDRG2 Increases Iodine Uptake and Inhibits Thyroid Carcinoma Cell Growth In Situ and In Vivo.

@article{Yin2016OverexpressionON,
  title={Overexpression of NDRG2 Increases Iodine Uptake and Inhibits Thyroid Carcinoma Cell Growth In Situ and In Vivo.},
  author={Anqi Yin and Chengguo Wang and Jiachen Sun and Jianjun Gao and Liang Tao and Xilin Du and Huadong Zhao and Jiandong Yang and Yan Li},
  journal={Oncology research},
  year={2016},
  volume={23 1-2},
  pages={43-51}
}
Medullary thyroid carcinoma (MTC) is an uncommon and highly aggressive tumor of the neuroendocrine system, which derives from the neuroendocrine C cells of the thyroid gland. Except for surgical resection, there are not very many effective systemic treatment options for MTC. N-Myc downstream-regulated gene 2 (NDRG2) had a significantly lower expression in MTC compared with normal thyroid tissue. However, the function of NDRG2 in MTC oncogenesis is largely unknown. In this study, we found that… CONTINUE READING