Overexpression of N-WASP in the brain of human epilepsy.

Abstract

Neuronal circuit remodeling is the most critical pathological characteristic closely associated with the initiation and maintenance of epilepsy; however, the exact mechanisms of neuronal remodeling need further elucidation. Neuronal Wiskott-Aldrich syndrome protein (N-WASP) is a key regulator of the actin cytoskeleton that causes actin polymerization and… (More)
DOI: 10.1016/j.brainres.2008.07.101

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