Overexpression of Muscarinic Receptor 3 Promotes Metastasis and Predicts Poor Prognosis in Non–Small-Cell Lung Cancer

@inproceedings{Lin2014OverexpressionOM,
  title={Overexpression of Muscarinic Receptor 3 Promotes Metastasis and Predicts Poor Prognosis in Non–Small-Cell Lung Cancer},
  author={Gengpeng Lin and Longhua Sun and Ran Wang and Yubiao B Guo and Canmao Xie},
  booktitle={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2014}
}
INTRODUCTION Chronic obstructive pulmonary disease (COPD) is an independent risk factor for lung cancer development, but the mechanism is not fully understood. Muscarinic receptor 3 (M3R) has been found to be involved in the progression of small-cell lung cancer and the pathological process of COPD. We hypothesized that M3R may contribute to lung cancer development, especially in patients with COPD. METHODS The correlation between M3R expression and clinical features of non-small-cell lung… CONTINUE READING
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