Overexpression of MicroRNA miR-30a or miR-191 in A549 Lung Cancer or BEAS-2B Normal Lung Cell Lines Does Not Alter Phenotype

@inproceedings{Patnaik2010OverexpressionOM,
  title={Overexpression of MicroRNA miR-30a or miR-191 in A549 Lung Cancer or BEAS-2B Normal Lung Cell Lines Does Not Alter Phenotype},
  author={Santosh Kumar Patnaik and Eric D. Kannisto and Sai S Yendamuri},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND MicroRNAs (miRNAs) are small, noncoding RNAs (ribonucleic acids) that regulate translation. Several miRNAs have been shown to be altered in whole cancer tissue compared to normal tissue when quantified by microarray. Based on previous such evidence of differential expression, we chose to study the functional significance of miRNAs miR-30a and -191 alterations in human lung cancer. METHODOLOGY/PRINCIPAL FINDINGS The functional significance of miRNAs miR-30a and -191 was studied by… CONTINUE READING

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