Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin.

Abstract

Pulmonary fibrosis is a common response to a variety of lung injuries, characterized by fibroblast/myofibroblast expansion and abnormal accumulation of extracellular matrix. An increased expression of matrix metalloprotease 9 (MMP9) in human and experimental lung fibrosis has been documented, but its role in the fibrotic response is unclear. We studied the… (More)

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Cite this paper

@article{Cabrera2007OverexpressionOM, title={Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin.}, author={Sandra Cabrera and Miguel Gaxiola and Jos{\'e} Luis Arreola and Remedios Ram{\'i}rez and Paul Jara and Jeanine M D'armiento and Thomas Richards and Mois{\'e}s Selman and Annie Pardo}, journal={The international journal of biochemistry & cell biology}, year={2007}, volume={39 12}, pages={2324-38} }