Overexpression of Hsp70 confers cytoprotection during gliadin exposure in Caco-2 cells

@article{BidmonFliegenschnee2015OverexpressionOH,
  title={Overexpression of Hsp70 confers cytoprotection during gliadin exposure in Caco-2 cells},
  author={Bettina Bidmon-Fliegenschnee and Hans Ch Lederhuber and Dagmar Csaicsich and Judith Pichler and Rebecca Herzog and Nima Memaran-Dadgar and W D Huber and Christoph Aufricht and Klaus Kratochwill},
  journal={Pediatric Research},
  year={2015},
  volume={78},
  pages={358-364}
}
Background:In Celiac disease (CD), cytoskeletal integrity of intestinal cells is disrupted by gliadin exposure. This study investigates the role of heat shock protein (Hsp)70 during cytoskeletal recovery in CD by assessing its induction and effects on junctional proteins.Methods:Using an in-vitro model of CD, cytoskeletal injury and recovery was assessed in… CONTINUE READING