Overexpression of HER-2/neu in endometrial cancer is associated with advanced stage disease.

Abstract

Prior studies have shown that overexpression of HER-2/neu occurs in one third of breast and ovarian cancers and that overexpression is associated with poor prognosis. We used a monoclonal antibody to assess immunohistochemically the level of HER-2/neu expression in normal and malignant endometrium. In 24 normal endometrial samples light to moderate (1+ to 2… (More)

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Cite this paper

@article{Berchuck1991OverexpressionOH, title={Overexpression of HER-2/neu in endometrial cancer is associated with advanced stage disease.}, author={Andy Berchuck and G. Rodriguez and Rhonda Kinney and Judith Soper and Randy Dodge and Daniel L. Clarke-Pearson and Robert C. Bast}, journal={American journal of obstetrics and gynecology}, year={1991}, volume={164 1 Pt 1}, pages={15-21} }