Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma.

@article{Uddin2012OverexpressionOF,
  title={Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma.},
  author={Shahab Uddin and Azhar R. Hussain and Maqbool Ahmed and Khawar Sohail Siddiqui and Fouad Hassan Al-Dayel and Prashant Bavi and Khawla S Al-Kuraya},
  journal={Haematologica},
  year={2012},
  volume={97 7},
  pages={1092-100}
}
BACKGROUND FoxM1 has been shown to play a critical role in the pathogenesis of various epithelial malignancies. However, its role in lymphoid malignancies has not been fully clarified. We, therefore, investigated the role of FoxM1 expression in a large cohort of diffuse large B-cell lymphoma samples and panel of cell lines. DESIGN AND METHODS FoxM1 expression was investigated in a large series of diffuse large B-cell lymphoma tissues in a tissue microarray format by immunohistochemistry… CONTINUE READING

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