Overexpression of Fascin-1 in Advanced Colorectal Adenocarcinoma: Tissue Microarray Analysis of Immunostaining Scores with Clinicopathological Parameters

Abstract

OBJECTIVE Fascin-1 is an actin-binding protein that promotes cell proliferation, adhesion and motility. We tested the hypothesis that fascin-1 expression correlates with clinicopathological parameters of colorectal adenocarcinomas. METHODS Immunohistochemical analysis of fascin-1 was performed in tissue microarrays of 91 surgical specimens, including 32… (More)

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