Overexpression of ERα inhibits proliferation and invasion of MKN28 gastric cancer cells by suppressing β-catenin.

@article{Zhou2013OverexpressionOE,
  title={Overexpression of ERα inhibits proliferation and invasion of MKN28 gastric cancer cells by suppressing β-catenin.},
  author={Ji-chun Zhou and Rong-yue Teng and Chaoyang Xu and Qinchuan Wang and Jufeng Guo and Chenpu Xu and Ziduo Li and Shu-duo Xie and Jianguo Shen and Linbo Wang},
  journal={Oncology reports},
  year={2013},
  volume={30 4},
  pages={
          1622-30
        }
}
The relationship between estrogen receptor (ER)α and patient prognosis has been identified in gastric cancer; however, the definite role of ERα in gastric cancer remains to be fully elucidated. The aim of the present in vitro study was to investigate the impact of ERα on cell proliferation, migration and invasion in gastric cancer cell lines. We investigated the biological effect of ERα overexpression on gastric carcinoma cells. An MKN28 gastric cancer cell line stably overexpressing ERα was… CONTINUE READING

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