Overexpression of CK20, MAP3K8 and EIF5A correlates with poor prognosis in early-onset colorectal cancer patients

@article{Tunca2013OverexpressionOC,
  title={Overexpression of CK20, MAP3K8 and EIF5A correlates with poor prognosis in early-onset colorectal cancer patients},
  author={Berrin Tunca and Gulçin Tezcan and Gulsah Cecener and Unal Egeli and Abdullah Zorluoğlu and Tuncay Yilmazlar and Seçil Ak and Omer Yerci and Ersin Ozturk and Gorkem Umut and Turkkan Evrensel},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2013},
  volume={139},
  pages={691-702}
}
Due to ethnic, genetic and environmental factors, the clinical and molecular characteristics of Turkish colorectal cancer (CRC) patients are different from those of Western populations. The aim of this study was to clarify the relevant alterations of gene expression associated with colorectal carcinogenesis in early-onset patients and to identify specific biomarkers that could provide novel therapeutic molecular targets in this population. The expression profiles of 114 different genes were… CONTINUE READING