Overexpression of Arabidopsis phytochelatin synthase paradoxically leads to hypersensitivity to cadmium stress.

@article{Lee2003OverexpressionOA,
  title={Overexpression of Arabidopsis phytochelatin synthase paradoxically leads to hypersensitivity to cadmium stress.},
  author={Sangman Lee and Jae Sun Moon and Tae-Seok Ko and David Petros and Peter B. Goldsbrough and Schuyler S. Korban},
  journal={Plant physiology},
  year={2003},
  volume={131 2},
  pages={
          656-63
        }
}
Phytochelatin (PC) plays an important role in heavy metal detoxification in plants and other living organisms. Therefore, we overexpressed an Arabidopsis PC synthase (AtPCS1) in transgenic Arabidopsis with the goal of increasing PC synthesis, metal accumulation, and metal tolerance in these plants. Transgenic Arabidopsis plants were selected, designated pcs lines, and analyzed for tolerance to cadmium (Cd). Transgenic pcs lines showed 12- to 25-fold higher accumulation of AtPCS1 mRNA, and… CONTINUE READING

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