Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.

@article{Delebecq2000OverexpressionLO,
  title={Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.},
  author={T J Delebecq and Henri Porte and Farid Zerimech and Marie Christine Copin and Val{\'e}rie Gouyer and Evelyne Dacquembronne and Malika Balduyck and Albrecht Wurtz and Guillaume Huet},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2000},
  volume={6 3},
  pages={1086-92}
}
Proteases contribute to tumor invasion and metastasis via their potential to degrade basement membranes and extracellular matrix. Our aim was to compare the level of several proteases: urokinase-type plasminogen activator (u-PA), matrix metalloproteinase 2 (MMP-2; 72-kDa type IV collagenase, also known as gelatinase A), MMP-11 [also known as stromelysin 3 (STR3)], and cathepsins B and L in resected non-small cell lung cancer. Between June 1996 and March 1998, samples of lung tumor tissues were… CONTINUE READING
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Changes in the expression of matrix proteases and of the transcription factor C-Ets-1 during progression of precancerous bronchial lesions

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